Factors affecting adherence with treatment advice in a clinical trial of patients with severe asthma.

ABSTRACT:

Background

Understanding why patients with severe asthma do not follow healthcare provider (HCP) advice to adjust treatment is critical to achieving personalised disease management.

Methods

We reviewed patient choice to follow HCP advice to adjust asthma treatment in a UK-based randomised, controlled, single-blind (study participant), multicentre, parallel group 48-week clinical study comparing biomarker-directed treatment adjustment with standard care in severe asthma.

Results

Of 1572 treatment advisories (291 participants), instructions were followed in 1377 cases (87.6%). Patients were more likely to follow advice to remain on treatment (96.7%) than to either reduce (70.3%) or increase (67.1%) their treatment, with 64% of patients following all treatment advice. Mu

SUBMITTER: Busby J 

PROVIDER: S-EPMC9202483 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature