Serum Testosterone Levels in 3-Month-Old Boys Predict Their Semen Quality as Young Adults.

ABSTRACT:

Context

It remains unknown how the postnatal activation of the hypothalamic-pituitary-gonadal axis in infancy, also known as "minipuberty", relates to adult testis function.

Objective

To investigate how markers of reproductive function in 3-month-old boys correlate with adult reproductive health parameters.

Methods

This population-based birth cohort study (the Copenhagen Mother-Child cohort), conducted at Copenhagen University Hospital, Denmark, included 259 boys examined once around 3 months of age and again at 18 to 20 years. Reproductive hormones, penile length, testis volume, and semen quality were analyzed. Minipubertal markers of testis function (by tertiles, T1-T3) were explored as predictors of adult semen quality using linear regression models. Associations b

SUBMITTER: Scheutz Henriksen L 

PROVIDER: S-EPMC9202716 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature