Review of pharmacotherapeutic treatments for primary sclerosing cholangitis.

ABSTRACT:

Background

The objective of this review was to evaluate pharmacotherapeutic treatments for primary sclerosing cholangitis (PSC) through a literature search of current published data. A review of the current clinical data for each treatment is discussed.

Methods

We conducted a systematic literature search for articles using EMBASE (1980 to April 1, 2018), and MEDLINE (1948 to April 1, 2018) using Ovid, to identify studies investigating various therapies in PSC. Search terms included the following: primary sclerosing cholangitis, cholangitis, sclerosing cholangitis; ursodeoxycholic acid, glucocorticoids, cyclosporine, tacrolimus, methotrexate, azathioprine, 6-mercaptopurine, penicillamine, anti-TNF

SUBMITTER: Zhang C 

PROVIDER: S-EPMC9202752 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature