Norovirus epidemiology in South African children <5 years hospitalised for diarrhoeal illness between 2009 and 2013.

ABSTRACT: Public health interest in norovirus (NoV) has increased in recent years following improved diagnostics, global burden estimates and the development of NoV vaccine candidates. This study aimed to describe the detection rate, clinical characteristics and environmental features associated with NoV detection in hospitalized children <5 years with diarrhoea in South Africa (SA). Between 2009 and 2013, prospective diarrhoeal surveillance was conducted at four sites in SA. Stool specimens were collected and screened for NoVs and other enteric pathogens using molecular and serological assays. Epidemiological and clinical data were compared in patients with or without detection of NoV. The study detected NoV in 15% (452/3103) of hospitalized children <5 years with diarrhoea with the majority of dis

SUBMITTER: Page NA 

PROVIDER: S-EPMC9203319 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature