Localised relative scotoma in cuticular drusen.

ABSTRACT:

Purpose

To investigate retinal sensitivity changes in eyes with pure cuticular drusen.

Methods

Multimodal imaging and microperimetry (37-loci grid) data were examined retrospectively to evaluate functional changes in eyes with pure cuticular drusen. Mean sensitivity in the cuticular drusen cohort was compared to age-matched normals. An age- and loci-specific normative reference was created to analyse localised sensitivity deviation.

Results

The mean number loci with relative scotoma in the cuticular drusen cohort (n = 27, mean [SD] age: 48.5 [12.4] years) referenced to normal eyes (n = 80, 53.5 [14.6] years) was 5.5 (95% confidence interval 3.0 to 8.1). However, mean sensitivity was not statistically different to the age-matched normal cohort (95% CI, - 2.3 to + 3.4 d

SUBMITTER: Charng J 

PROVIDER: S-EPMC9203397 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature