Digital biomarkers and sex impacts in Alzheimer's disease management - potential utility for innovative 3P medicine approach.

ABSTRACT: Digital biomarkers are defined as objective, quantifiable physiological and behavioral data that are collected and measured by means of digital devices. Their use has revolutionized clinical research by enabling high-frequency, longitudinal, and sensitive measurements. In the field of neurodegenerative diseases, an example of a digital biomarker-based technology is instrumental activities of daily living (iADL) digital medical application, a predictive biomarker of conversion from mild cognitive impairment (MCI) due to Alzheimer's disease (AD) to dementia due to AD in individuals aged 55 + . Digital biomarkers show promise to transform clinical practice. Nevertheless, their use may be affected by variables such as demographics, genetics, and phenotype. Among these factors, sex is particula

SUBMITTER: Harms RL 

PROVIDER: S-EPMC9203627 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature