903 Protein Saver cards: the best alternative for dried blood spot storage at room temperature for HCV RNA.

ABSTRACT: Hepatitis C virus (HCV) infection remains a global health problem, detected only in the early stages by molecular tests. Molecular tests detect HCV RNA, which is very prone to degradation by ribonucleases, reason why blood samples must be transported and stored at - 20 °C, or even - 70 °C for long-term storage. Flinders Technology Associates (FTA) cards are a useful sampling collecting device for dry blood spot (DBS) storage, especially for low and middle-income countries (LMIC). In this study, we analyzed viral HCV RNA integrity for long-term storage at room temperature compared to - 20 °C using two different types of cards for DBS: FTA Classic and 903 Protein Saver cards. For this purpose, DBS were prepared on these cards using blood or plasma samples from HCV infected patients, and samp

SUBMITTER: Arca-Lafuente S 

PROVIDER: S-EPMC9203708 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature