Association Between Digoxin Use and Cardiac Function in Infants With Single-Ventricle Congenital Heart Disease During the Interstage Period.

ABSTRACT:

Objectives

To examine the association between digoxin use and cardiac function assessed by echocardiographic indices in infants with single-ventricle (SV) congenital heart disease (CHD) during the interstage period.

Design

Retrospective cohort study.

Setting

Fifteen North American hospitals.

Patients

Infants discharged home following stage 1 palliation (S1P) and prior to stage 2 palliation (S2P). Infants with no post-S1P and pre-S2P echocardiograms were excluded.

Interventions

None.

Measurements and main results

Of 373 eligible infants who met inclusion criteria, 140 (37.5%) were discharged home on digoxin. In multivariable linear and logistic regressions, we found that compared with infants discharged home without digoxin, those discharged with d

SUBMITTER: Kumar KR 

PROVIDER: S-EPMC9203926 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature