Polypharmacy Is Associated With Falls in Women With and Without HIV.

ABSTRACT:

Background

Aging in people with HIV is associated with increased risk of developing synergistic conditions such as neurocognitive impairment, polypharmacy, and falls. We assessed associations between polypharmacy (use of 5 or more non-ART medications), use of neurocognitive adverse effects (NCAE) medications, and odds of falls in women with HIV (WWH) and without HIV (HIV-).

Methods

Self-reported falls and medication use data were contributed semiannually by 1872 (1315 WWH and 557 HIV-) Women's Interagency HIV Study participants between 2014 and 2016. Polypharmacy and NCAE medication use were evaluated separately and jointly in multivariable models to assess their independent contributions to single and multiple falls risk.

Results

The proportion of women who reported

SUBMITTER: Psomas CK 

PROVIDER: S-EPMC9203977 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature