Shortwave infrared spatial frequency domain imaging for non-invasive measurement of tissue and blood optical properties.

ABSTRACT:

Significance

The shortwave infrared (SWIR) optical window (∼900 to 2000 nm) has attracted interest for deep tissue imaging due to the lower scattering of light. SWIR spatial frequency domain imaging (SWIR SFDI) provides wide-field tissue optical property measurements in this wavelength band. Key design and performance characteristics, such as portability, wavelength selection, measurement resolution, and the effect of skin have not yet been addressed for SWIR SFDI.

Aim

To fabricate and characterize a SWIR SFDI system for clinical use.

Approach

The optimal choice of wavelengths was identified based on optical property uncertainty estimates and imaging depth. A compact light-emitting diode-based dual wavelength SWIR SFDI system was fabricated. A two-layer inverse model

SUBMITTER: Pilvar A 

PROVIDER: S-EPMC9204261 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature