Relationship between serum insulin-like growth factor 1 levels and ischaemic stroke: a systematic review and meta-analysis.

ABSTRACT:

Objective

To assess the association of insulin-like growth factor 1 (IGF-1) with the risk of incident ischaemic stroke and outcome after ischaemic stroke.

Design

A systematic review of primary studies.

Setting

Hospitals in Western Sweden, Italy, China and Denmark.

Methods

A search was carried out in eligible studies in electronic databases (PubMed, Scopus, Embase, China National Knowledge Infrastructure and Web of Science) updated to 29 December 2020. The relevant data were extracted in order to conduct the meta-analysis. Review Manager V.5.2 was used to pool data and calculate the mean difference (MD) and its 95% CI. Heterogeneity, subgroup analysis, sensitivity analysis and publication bias were also performed in this meta-analysis.

Results

A total of

SUBMITTER: Li Y 

PROVIDER: S-EPMC9204407 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature