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Steroid use for established bronchopulmonary dysplasia: study protocol for a systematic review and meta-analysis.


ABSTRACT:

Introduction

Postnatal steroids during the first few weeks of life have been demonstrated to be effective in decreasing the incidence of bronchopulmonary dysplasia (BPD), a serious chronic respiratory condition affecting preterm infants. However, this preventive option is limited by the concern of neurological side effects. Steroids are used to treat established BPD in an attempt to reduce mortality, and length of stay and home oxygen therapy, both of which associated with high levels of parental stress and healthcare costs. Moreover, a late timing for steroid treatment may show a more favourable safety profile in terms of neurodevelopment outcomes, considering the added postnatal brain maturation of these infants. Here, we report a protocol for a systematic review, which aims to d

SUBMITTER: Strashun S 

PROVIDER: S-EPMC9204409 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature