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2,7-Diaminobenzopyrylium Dyes Are Live-Cell Mitochondrial Stains.

ABSTRACT: Small-molecule fluorescent stains enable the imaging of cellular structures without the need for genetic manipulation. Here, we introduce 2,7-diaminobenzopyrylium (DAB) dyes as live-cell mitochondrial stains excited with violet light. This amalgam of the coumarin and rhodamine fluorophore structures yields dyes with high photostability and tunable spectral properties.

SUBMITTER: Banala S

PROVIDER: S-EPMC9204777 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature

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2,7-Diaminobenzopyrylium Dyes Are Live-Cell Mitochondrial Stains.

Banala Sambashiva S Tkachuk Ariana N AN Patel Ronak R Kumar Pratik P Brown Timothy A TA Lavis Luke D LD

ACS bio & med chem Au 20220228 3

Small-molecule fluorescent stains enable the imaging of cellular structures without the need for genetic manipulation. Here, we introduce 2,7-diaminobenzopyrylium (DAB) dyes as live-cell mitochondrial stains excited with violet light. This amalgam of the coumarin and rhodamine fluorophore structures yields dyes with high photostability and tunable spectral properties. ...[more]

PMID: 35726328

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