Highly efficient magnetic ablation and the contrast of various imaging using biocompatible liquid-metal gallium.

ABSTRACT:

Background

Although the powerful clinical effects of radiofrequency and microwave ablation have been established, such ablation is associated with several limitations, including a small ablation size, a long ablation time, the few treatment positioning, and biosafety risks. To overcome these limitations, biosafe and efficient magnetic ablation was achieved in this study by using biocompatible liquid gallium as an ablation medium and a contrast medium for imaging.

Results

Magnetic fields with a frequency (f) lower than 200 kHz and an amplitude (H) × f value lower than 5.0 × 10⁹ Am^-1 s^-1 were generated using the proposed method. These fields could generate an ablation size of 3 cm in rat liver lobes under a temperature of approximately 300 °C a

SUBMITTER: Lee CW 

PROVIDER: S-EPMC9205100 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature