Antibody Response to COVID-19 Booster Vaccination in Healthcare Workers.

ABSTRACT:

Objective

To evaluate the mean increase of anti-S IgG antibody titer between the basal, pre-booster level to the titer assessed 14 days after the booster dose of BNT162b2.

Patients and methods

The RENAISSANCE study is an observational, longitudinal, prospective, population-based study, conducted on healthcare workers of Niguarda Hospital in Milan, Italy who received a BNT162b2 booster dose at least 180 days after their second dose or after positivity for SARS-CoV-2 and accepted to take part in the study. The RENAISSANCE study was conducted from January 1, 2021 through December 28, 2021.

Findings

1,738 subjects were enrolled among healthcare workers registered for the booster administration at our hospital. Overall, 0.4% of subjects were seronegative at the pre-booster

SUBMITTER: Pani A 

PROVIDER: S-EPMC9205631 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature