Which Sugar to Take and How Much to Take? Two Distinct Decisions Mediated by Separate Sensory Channels.

ABSTRACT: In Drosophila melanogaster, gustatory receptor neurons (GRNs) for sugar taste coexpress various combinations of gustatory receptor (Gr) genes and are found in multiple sites in the body. To determine whether diverse sugar GRNs expressing different combinations of Grs have distinct behavioral roles, we examined the effects on feeding behavior of genetic manipulations which promote or suppress functions of GRNs that express either or both of the sugar receptor genesGr5a (Gr5a+ GRNs) and Gr61a (Gr61a+ GRNs). Cell-population-specific overexpression of the wild-type form of Gr5a (Gr5a⁺ ) in the Gr5a mutant background revealed that Gr61a+ GRNs localized on the legs and internal mouthpart critically contribute

SUBMITTER: Kohatsu S 

PROVIDER: S-EPMC9206540 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature