Preoperative Computed Tomography Angiography Reveals Leaflet-Specific Calcification and Excursion Patterns in Aortic Stenosis.

ABSTRACT:

Background

Computed tomography-based evaluation of aortic stenosis (AS) by calcium scoring does not consider interleaflet differences in leaflet characteristics. Here, we sought to examine the functional implications of these differences.

Methods

We retrospectively reviewed the computed tomography angiograms of 200 male patients with degenerative calcific AS undergoing transcatheter aortic valve replacement and 20 male patients with normal aortic valves. We compared the computed tomography angiography (CTA)-derived aortic valve leaflet calcification load (AVLC_CTA), appearance, and systolic leaflet excursion (LE_sys) of individual leaflets. We performed computer simulations of normal valves to investigate how interleaflet differences in LE_sys a

SUBMITTER: Chen IY 

PROVIDER: S-EPMC9206593 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature