Multi-phase contrast-enhanced magnetic resonance image-based radiomics-combined machine learning reveals microscopic ultra-early hepatocellular carcinoma lesions.

ABSTRACT:

Purpose

This study aimed to investigate whether models built from radiomics features based on multiphase contrast-enhanced MRI can identify microscopic pre-hepatocellular carcinoma lesions.

Methods

We retrospectively studied 54 small hepatocellular carcinoma (SHCC, diameter < 2 cm) patients and 70 patients with hepatocellular cysts or haemangiomas from September 2018 to June 2021. For the former, two MRI scans were collected within 12 months of each other; the 2^nd scan was used to confirm the diagnosis. The volumes of interest (VOIs), including SHCCs and normal liver tissues, were delineated on the 2^nd scans, mapped to the 1^st scans via image registration, and enrolled into the SHCC and internal-control cohorts, respectively, while those of n

SUBMITTER: Sun K 

PROVIDER: S-EPMC9206604 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature