Aging gut microbiota of wild macaques are equally diverse, less stable, but progressively personalized.

ABSTRACT:

Background

Pronounced heterogeneity of age trajectories has been identified as a hallmark of the gut microbiota in humans and has been explained by marked changes in lifestyle and health condition. Comparatively, age-related personalization of microbiota is understudied in natural systems limiting our comprehension of patterns observed in humans from ecological and evolutionary perspectives.

Results

Here, we tested age-related changes in the diversity, stability, and composition of the gut bacterial community using 16S rRNA gene sequencing with dense repeated sampling over three seasons in a cross-sectional age sample of adult female Assamese macaques (Macaca assamensis) living in their natural forest habitat. Gut bacterial composition exhibited a personal signature which be

SUBMITTER: Sadoughi B 

PROVIDER: S-EPMC9206754 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature