Serum pepsinogen: A potential non-invasive screening method for moderate and severe atrophic gastritis among an asian population.

ABSTRACT:

Background

Serum pepsinogen has been approved and used widely as an effective biomarker in diagnosis of atrophic gastritis and gastric cancer; however, its validity and appropriate cut-off values vary among different populations. This study aimed to initially assess the diagnostic value of the serum pepsinogen in diagnosis of moderate and severe atrophic gastritis for Vietnamese population.

Materials and methods

A cross-sectional study enrolled 273 participants from June 2008 to November 2019. All participants underwent a gastroscopy procedure and three tests including serum PG test, pathology test, and Hp-Igg Elisa test. The Kimura-Takemoto classification and OLGA system were used to classify the mild versus moderate-severe atrophic gastritis. Receiver Operating Characteris

SUBMITTER: Nguyen CL 

PROVIDER: S-EPMC9207076 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature