Two cases of Erythrodermic psoriasis treated with Golimumab.

ABSTRACT:

Introduction and importance

Erythrodermic psoriasis (EP) is a very severe subtype of psoriasis, with a challenge poses in its treatment, as currently available therapies often provide unsatisfactory results, for those many biologics have been used in the treatment of EP such as Golimumab which has been extensively studied for the treatment of psoriatic arthritis, and chronic plaque psoriasis. However, no clinical trials have been performed for EP.

Case presentation

We report two cases of a 23-year old female, and a 31-year male who presented with severe psoriasis that previously un respond to ultraviolet B phototherapy, methotrexate, cyclosporine, and topical agents. Skin lesions worsened progressively and developed into erythroderma. Therefore, we administered golimumab 50 

SUBMITTER: Kudsi M 

PROVIDER: S-EPMC9207129 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature