A Radiomics Model for Preoperative Predicting Sentinel Lymph Node Metastasis in Breast Cancer Based on Dynamic Contrast-Enhanced MRI

ABSTRACT:

Purpose

To develop a radiomics model based on preoperative dynamic contrast-enhanced MRI (DCE-MRI) to identify sentinel lymph node (SLN) metastasis in breast cancer (BC) patients.

Materials and Methods

The MRI images and clinicopathological data of 142 female primary BC patients from January 2017 to December 2018 were included in this study. The patients were randomly divided into the training and testing cohorts at a ratio of 7:3. Four types of radiomics models were built: 1) a radiomics model based on the region of interest (ROI) of breast tumor; 2) a radiomics model based on the ROI of intra- and peri-breast tumor; 3) a radiomics model based on the ROI of axillary lymph node (ALN); 4) a radiomics model based on the ROI of ALN and breast tumor. Receiver operating charac

SUBMITTER: Ma M 

PROVIDER: S-EPMC9207247 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature