Mechanistic Understanding of Lung Inflammation: Recent Advances and Emerging Techniques.

ABSTRACT: Acute respiratory distress syndrome (ARDS) is a life-threatening lung injury characterized by an acute inflammatory response in the lung parenchyma. Hence, it is considered as the most appropriate clinical syndrome to study pathogenic mechanisms of lung inflammation. ARDS is associated with increased morbidity and mortality in the intensive care unit (ICU), while no effective pharmacological treatment exists. It is very important therefore to fully characterize the underlying pathobiology and the related mechanisms, in order to develop novel therapeutic approaches. In vivo and in vitro models are important pre-clinical tools in biological and medical research in the mechanistic and pathological understanding of the majority of diseases. In this review, we will present data from selected ex

SUBMITTER: Keskinidou C 

PROVIDER: S-EPMC9207257 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature