Influence of the Human Lipidome on Epicardial Fat Volume in Mexican American Individuals.

ABSTRACT:

Introduction

Cardiovascular disease (CVD) is the leading cause of mortality worldwide and is the leading cause of death in the US. Lipid dysregulation is a well-known precursor to metabolic diseases, including CVD. There is a growing body of literature that suggests MRI-derived epicardial fat volume, or epicardial adipose tissue (EAT) volume, is linked to the development of coronary artery disease. Interestingly, epicardial fat is also actively involved in lipid and energy homeostasis, with epicardial adipose tissue having a greater capacity for release and uptake of free fatty acids. However, there is a scarcity of knowledge on the influence of plasma lipids on EAT volume.

Aim

The focus of this study is on the identification of novel lipidomic species associated with CMRI-d

SUBMITTER: Leandro AC 

PROVIDER: S-EPMC9207321 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature