Multimodal data fusion of cortical-subcortical morphology and functional network connectivity in psychotic spectrum disorder.

ABSTRACT: Multiple authors have noted overlapping symptoms and alterations across clinical, anatomical, and functional brain features in schizophrenia (SZ), schizoaffective disorder (SZA), and bipolar disorder (BPI). However, regarding brain features, few studies have approached this line of inquiry using analytical techniques optimally designed to extract the shared features across anatomical and functional information in a simultaneous manner. Univariate studies of anatomical or functional alterations across these disorders can be limited and run the risk of omitting small but potentially crucial overlapping or joint neuroanatomical (e.g., structural images) and functional features (e.g., fMRI-based features) which may serve as informative clinical indicators of across multiple diagnostic categori

SUBMITTER: DeRamus TP 

PROVIDER: S-EPMC9207350 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature