Left Atrial Appendage Occlusion as an Alternative to Anticoagulants in Ibrutinib-Induced Hemorrhagic Pericardial Effusion.

ABSTRACT: Bleeding tendency increases with concomitant use of ibrutinib and anticoagulants. Our patient presented with shortness of breath and was found to have a nonmalignant hemorrhagic pericardial effusion. Ibrutinib was resumed, and percutaneous left atrial appendage occlusion was performed as a substitute for the chemical anticoagulation to decrease the drug-drug interaction. (Level of Difficulty: Intermediate.).

SUBMITTER: Jeelani H 

PROVIDER: S-EPMC9207956 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature