Association Between Circulating Regulator of Calcineurin 2 Concentrations With Overweight and Obesity.

ABSTRACT:

Background

Regulator of calcineurin 2 (RCAN2) has been reported to promote food intake and weight gain in animal studies. However, its effect on body weight in humans is unclear.

Objective

This study aimed to investigate the relationship between serum RCAN2 concentrations and participants with overweight/obesity.

Methods

A cross-sectional study was performed in 872 Chinese adults, including 348 participants with normal weight (NW), 397 participants with overweight (OW), and 127 participants with obesity (OB). All participants were divided into NW, OW and OB groups according to their body mass index (BMI). Serum RCAN2 concentrations were determined by enzyme-linked immunosorbent assay.

Results

Serum RCAN2 concentrations gradually increased with the increase of B

SUBMITTER: Wang H 

PROVIDER: S-EPMC9208054 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature