Defensins as a promising class of tick antimicrobial peptides: a scoping review.

ABSTRACT:

Background

Ticks are hematophagous parasites that transmit an extensive range of pathogens to their vertebrate hosts. Ticks can destroy invading microorganisms or alleviate infection via their rudimentary but orchestrated innate immune system. Antimicrobial peptides (AMPs) are important components of tick innate immunity. Among these humoral effector molecules, defensins are well-studied and widely identified in various species of Ixodidae (hard ticks) and Argasidae (soft ticks). This review was aimed at presenting the characterization of tick defensins from structure-based taxonomic status to antimicrobial function.

Main text

All published papers written in English from 2001 to May 2022 were searched through PubMed and Web of Science databases with the combination of releva

SUBMITTER: Wu J 

PROVIDER: S-EPMC9208123 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature