Risk factors for discontinuing oral immunotherapy in children with persistent cow milk allergy.

ABSTRACT:

Background

There are no universally accepted criteria for discontinuing milk oral immunotherapy (MOIT) in patients with persistent cow milk allergy (CMA) and little data are available on predictive risk factors for dropping out from oral immunotherapy (OIT), due to allergic reactions or other reasons.

Methods

We retrospectively reviewed clinical records of patients with persistent severe CMA undergoing MOIT in a tertiary care center hospital to investigate risk factors associated with discontinuation of OIT. Persistent and severe allergy was defined as the history of systemic reactions and any milk protein-specific IgE level >85 kU/ml. All patients were first admitted for an in-hospital rush phase eventually followed by an at-home dose increase. We evaluated the effect of va

SUBMITTER: Benelli E 

PROVIDER: S-EPMC9208286 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature