Computer-aided detection and abnormality score for the outer retinal layer in optical coherence tomography.

ABSTRACT:

Background

To develop computer-aided detection (CADe) of ORL abnormalities in the retinal pigmented epithelium, interdigitation zone and ellipsoid zone via optical coherence tomography (OCT).

Methods

In this retrospective study, healthy participants with normal ORL, and patients with abnormality of ORL including choroidal neovascularisation (CNV) or retinitis pigmentosa (RP) were included. First, an automatic segmentation deep learning (DL) algorithm, CADe, was developed for the three outer retinal layers using 120 handcraft masks of ORL. This automatic segmentation algorithm generated 4000 segmentations, which included 2000 images with normal ORL and 2000 (1000 CNV and 1000 RP) images with focal or wide defects in ORL. Second, based on the automatically generated segmentati

SUBMITTER: Rim TH 

PROVIDER: S-EPMC9208332 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature