Neurodevelopmental consequences of early plasma sodium changes in very preterm infants.

ABSTRACT:

Background

Sodium fluctuations in very preterm neonates and their neurodevelopmental consequences are not well described.

Methods

We assessed the changes in plasma sodium and glucose in the first days of life in very preterm neonates and studied the association of glucose-corrected plasma sodium fluctuations on neurodevelopmental outcomes. We included 147 consecutive neonates born before 29 weeks of gestation in our center and retrospectively obtained plasma sodium, glucose, and glucose-corrected sodium levels. Neurodevelopmental assessment was obtained from the Canadian Neonatal Follow-Up Network.

Results

Mean ± standard deviation of plasma sodium changes within the first 10 days of life were 16.2 ± 6.0, 14.8 ± 5.3, and 11.1 ± 5.2 mmol/l in neonates born ≤25, 25-26,

SUBMITTER: Gervais AS 

PROVIDER: S-EPMC9208708 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature