Evaluation of the Benefits and Harms of Lung Cancer Screening With Low-Dose Computed Tomography: Modeling Study for the US Preventive Services Task Force.

ABSTRACT:

Importance

The US Preventive Services Task Force (USPSTF) is updating its 2013 lung cancer screening guidelines, which recommend annual screening for adults aged 55 through 80 years who have a smoking history of at least 30 pack-years and currently smoke or have quit within the past 15 years.

Objective

To inform the USPSTF guidelines by estimating the benefits and harms associated with various low-dose computed tomography (LDCT) screening strategies.

Design, setting, and participants

Comparative simulation modeling with 4 lung cancer natural history models for individuals from the 1950 and 1960 US birth cohorts who were followed up from aged 45 through 90 years.

Exposures

Screening with varying starting ages, stopping ages, and screening frequency. Eligibility

SUBMITTER: Meza R 

PROVIDER: S-EPMC9208912 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature