Development and internal validation of a model to predict type 2 diabetic complications after gestational diabetes.

ABSTRACT: Gestational diabetes mellitus (GDM) increases the risk of early-onset type 2 diabetes, which further exacerbates the risk of developing diabetic complications such as kidney, circulatory, and neurological complications. Yet, existing models have solely focused on the prediction of type 2 diabetes, and not of its complications, which are arguably the most clinically relevant outcomes. Our aim was to develop a prediction model for type 2 diabetic complications in patients with GDM. Using provincial administrative data from Quebec, Canada, we developed a model to predict type 2 diabetic complications within 10 years among 90,143 women with GDM. The model was internally validated and assessed for discrimination, calibration, and risk stratification accuracy. The incidence of diabetic complicat

SUBMITTER: Ukah UV 

PROVIDER: S-EPMC9209541 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature