Generation of a human induced pluripotent stem cell line from a patient diagnosed with schizophrenia carrying a 16p11.2 deletion.

ABSTRACT: 16p11.2 copy number variations have been associated with neurodevelopmental disorders. Human induced pluripotent stem cells were generated from fibroblasts obtained from a patient diagnosed with schizophrenia with a 16p11.2 deletion. The generated cell line was further validated for its pluripotency and potential to differentiate into the three germ layers.

SUBMITTER: Madencioglu DA 

PROVIDER: S-EPMC9209596 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature