Histopathological role of vitamin D deficiency in recurrent/chronic tonsillitis pathogenesis: Vascular epithelial growth factor-mediated angiogenesis in tonsil.

ABSTRACT:

Objectives

Our aim in this study is to reveal the role of vitamin D deficiency in the pathogenesis of recurrent/chronic tonsillitis and to determine the expression of vascular epithelial growth factor (VEGF).

Material and methods

This study was conducted between September and February. Thirty-two patients between the ages of 3 and 35 (mean age 9.71) with recurrent episodes of chronic tonsillitis were selected. Patients were divided into four groups according to their 25OHD levels. Patients with 25OHD levels 0-10 ng/ml were determined as Group 1, 11-20 ng/ml Group 2, 21-30 ng/ml Group 3, and 31-50 ng/ml control Group 4. Routine histological tissue sampling was performed for histopathological evaluation of the tonsillar tissues under light microscope (LM). Five micron sections

SUBMITTER: Safak AS 

PROVIDER: S-EPMC9209805 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature