Review on development of potential inhibitors of SARS-CoV-2 main protease (M^Pro).

ABSTRACT:

Background

The etiological agent for the coronavirus illness outbreak in 2019-2020 is a novel coronavirus known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (COVID-19), whereas coronavirus disease pandemic of 2019 (COVID-19) has compelled the implementation of novel therapeutic options.

Main body of the abstract

There are currently no targeted therapeutic medicines for this condition, and effective treatment options are quite restricted; however, new therapeutic candidates targeting the viral replication cycle are being investigated. The primary protease of the severe acute respiratory syndrome coronavirus 2 virus is a major target for therapeutic development (M^Pro). Severe acute respiratory syndrome coronavirus 2, severe acute respiratory syndr

SUBMITTER: Katre SG 

PROVIDER: S-EPMC9209839 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature