Distribution equality as an optimal epidemic mitigation strategy.

ABSTRACT: Upon the development of a therapeutic, a successful response to a global pandemic relies on efficient worldwide distribution, a process constrained by our global shipping network. Most existing strategies seek to maximize the outflow of the therapeutics, hence optimizing for rapid dissemination. Here we find that this intuitive approach is, in fact, counterproductive. The reason is that by focusing strictly on the quantity of disseminated therapeutics, these strategies disregard the way in which this quantity distributes across destinations. Most crucially-they overlook the interplay of the therapeutic spreading patterns with those of the pathogens. This results in a discrepancy between supply and demand, that prohibits efficient mitigation even under optimal conditions of superfluous flow

SUBMITTER: Hacohen A 

PROVIDER: S-EPMC9210068 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature