Estimation of cardiac QTc intervals in people prescribed antipsychotics: a comparison of correction factors.

ABSTRACT:

Background

A prolonged electrocardiogram (ECG) QT interval is associated with cardiac events and increased mortality. Antipsychotics can prolong the QT interval. The QT interval requires correction (QTc) for heart rate using a formula or QT-nomogram. The QT and QTc can be calculated automatically by the ECG machine or manually; however, machine-measured QT(c) intervals may be inaccurate.

Objective

We aimed to investigate the mean QTc and proportion of prolonged QTc intervals in people taking antipsychotic medicines.

Methods

We conducted an observational retrospective chart review and data analysis of all consecutive patients taking antipsychotics, with an ECG record, admitted to the psychiatric unit of a large tertiary hospital in Brisbane, Australia, between 1 Januar

SUBMITTER: Andric T 

PROVIDER: S-EPMC9210090 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature