Dermatologic manifestations in paediatric neurofibromatosis type 2: a cross sectional descriptive multicentric study.

ABSTRACT:

Background

Neurofibromatosis type 2 (NF2) is characterized by bilateral vestibular schwannoma (VS) more often in adults but a severe paediatric form with multiple neurological tumours is also described. In this population, a early diagnosis is important to prevent the onset of neurological complications but is difficult, particularly without a familial history. Cutaneous manifestations, which may precede VS or neurological tumours by several years, may contribute to an early diagnosis, but specific studies are lacking. The objective of this study was to characterize cutaneous manifestations of NF2 in a paediatric population.

Results

This observational, descriptive and multicentric study was conducted from April 2019 to April 2020 in seven academic French hospitals. We includ

SUBMITTER: Legoupil S 

PROVIDER: S-EPMC9210598 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature