Safety of endoscopic mucosal resection of large colonic polyps in elderly patients: a systematic review and meta-analysis.

ABSTRACT:

Background

Endoscopic mucosal resection (EMR) is a procedure commonly used for large sessile and flat polyps. However, it may cause bleeding, perforation, and complications related to anesthesia. There are limited data on the safety and efficacy of EMR in the elderly. Therefore, we conducted a comprehensive review and meta-analysis to assess EMR safety in elderly patients.

Methods

We searched MEDLINE, Embase, Cochrane Central Register of Controlled Trials, and Web of Science Core Collection for studies evaluating EMR for large colorectal lesions (>20 mm) in older patients (75+ years). Our primary result was post-polypectomy bleeding and perforation, while our secondary outcome was recurrence or residual polyp.

Results

The meta-analysis included 6 studies with 2903 pat

SUBMITTER: Iqbal U 

PROVIDER: S-EPMC9210775 | biostudies-literature | 2022 Jul-Aug

REPOSITORIES: biostudies-literature