Pulmonary lymphomatoid granulomatosis in a 4-year-old girl: A case report.

ABSTRACT:

Background

Pulmonary lymphomatoid granulomatosis (PLG) is a lymphoproliferative disease associated with Epstein-Barr viral infection occurring mainly in adults and rarely in children. It is characterized by multiple pulmonary nodules. Its diagnosis depends on lung biopsy findings. Most patients are immunodeficient, and it commonly presents in children undergoing chemotherapy for leukemia. We report the case of a child with PLG caused by a mutation in the macrophage-expressed gene 1 (MPEG1), suggesting possible PLG occurrence in children undergoing treatment for pulmonary nodular lesions.

Case summary

This study reports a case of PLG without apparent immunodeficiency, suggesting the possibility of this disease occurrence during the treatment of pulmonary nodular lesions in ch

SUBMITTER: Yao JW 

PROVIDER: S-EPMC9210899 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature