Clinical helminth infections alter host gut and saliva microbiota.

ABSTRACT:

Background

Previous reports show altered gut bacterial profiles are associated with helminth infected individuals. Our recently published molecular survey of clinical helminthiases in Thailand border regions demonstrated a more comprehensive picture of infection prevalence when Kato Katz microscopy and copro-qPCR diagnostics were combined. We revealed that Opisthorchis viverrini, hookworm, Ascaris lumbricoides and Trichuris trichiura were the most predominant helminth infections in these regions. In the current study, we have profiled the faecal and saliva microbiota of a subset of these helminth infected participants, in order to determine if microbial changes are associated with parasite infection.

Methods

A subset of 66 faecal samples from Adisakwattana et al., (2020) wer

SUBMITTER: Gobert GN 

PROVIDER: S-EPMC9212162 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature