An exploratory study of factors associated with long-term, high-dose opioid prescription in cancer patients in Japan based on a medical claims database.

ABSTRACT:

Purpose

As the cancer survivors increase, patients using long-term and high-dose opioids are also increasing. Therefore, the promotion of appropriate use is important. This study investigated the actual status of opioid prescriptions in Japan and identified factors associated with long-term, high-dose prescription.

Methods

We conducted a case-control study using a hospital-based administrative claims database. Patients with a diagnosis of cancer and prescriptions of opioids were included. Patients who received continuous opioid for less than 183 days were defined as the "control," and patients who received continuous opioid at higher dose levels (≥ 120 mg/day of oral morphine equivalent) for 183 days or more were defined as the "case." The case was subdivided into two groups

SUBMITTER: Hashimoto T 

PROVIDER: S-EPMC9213265 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature