Circulating testosterone and dehydroepiandrosterone are associated with individual motor unit features in untrained and highly active older men.

ABSTRACT: Long-term exercise training has been considered as an effective strategy to counteract age-related hormonal declines and minimise muscle atrophy. However, human data relating circulating hormone levels with motor nerve function are scant. The aims of the study were to explore associations between circulating sex hormone levels and motor unit (MU) characteristics in older men, including masters athletes competing in endurance and power events. Forty-three older men (mean ± SD age: 69.9 ± 4.6 years) were studied based on competitive status. The serum concentrations of dehydroepiandrosterone (DHEA), total testosterone (T) and estradiol were quantified using liquid chromatography mass spectrometry. Intramuscular electromyographic signals were recorded from vastus lateralis (VL) during 25% of m

SUBMITTER: Guo Y 

PROVIDER: S-EPMC9213614 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature