Connecting research and teaching introductory cell and molecular biology using an Arabidopsis mutant screen.

ABSTRACT: A complex research project was translated into a Course-based Undergraduate Research Experience (CURE), which was implemented in sections of an introductory Cell and Molecular Biology laboratory course. The research laboratory generated an engineered plant line producing a growth-inhibiting, lipid-derived plant hormone and mutagenized this line. Students in the CURE cultured the mutagenized plant population and selected and characterized suppressor mutants. They learned to observe phenotypes related to the biosynthesis and perception of the plant hormone and explored the genetic and biochemical basis of these phenotypes. As the students studied the relevant genetic, molecular and biochemical concepts during this CURE, they were able to translate this knowledge into practice and develop sci

SUBMITTER: Liu J 

PROVIDER: S-EPMC9214838 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature