Quantitative analysis of diffusion weighted imaging in rectal cancer during radiotherapy using a magnetic resonance imaging integrated linear accelerator.

ABSTRACT:

Background and purpose

Magnetic resonance imaging integrated linear accelerator (MR-Linac) platforms enable acquisition of diffusion weighted imaging (DWI) during treatment providing potential information about treatment response. Obtaining DWI on these platforms is technically different from diagnostic magnetic resonance imaging (MRI) scanners. The aim of this project was to determine feasibility of obtaining DWI and calculating apparent diffusion coefficient (ADC) parameters longitudinally in rectal cancer patients on the MR-Linac.

Materials and methods

Nine patients undergoing treatment on MR-Linac had DWI acquired using b-values 0, 30, 150, 500 s/mm². Gross tumour volume (GTV) and normal tissue was delineated on DWI throughout treatment and median ADC was calc

SUBMITTER: Ingle M 

PROVIDER: S-EPMC9214864 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature