Effect of Exercise Training on 1,25(OH)₂D Levels: The FIT-AGEING Randomized Controlled Trial.

ABSTRACT:

Background

Vitamin D deficiency is currently endemic worldwide and is considered as an important factor in the development of several chronic conditions. Physical exercise has been postulated as an auspicious strategy to counteract age-related disorders preventing premature mortality. However, the effects of chronic exercise training on 1,25-dihydroxyvitamin D [1,25(OH)₂D] is unclear. This 12-week randomized controlled trial aimed to investigate the effects of different training modalities on 1,25(OH)₂D in healthy sedentary adults.

Hypothesis

Exercise training will increase 1,25(OH)₂D in the study cohort.

Study design

Randomized controlled clinical trial.

Level of evidence

Level 1.

Methods

A total of 89 healthy sedentary

SUBMITTER: De-la-O A 

PROVIDER: S-EPMC9214904 | biostudies-literature | 2022 Jul-Aug

REPOSITORIES: biostudies-literature