Mortality-associated clinical risk factors in patients with febrile neutropenia: A retrospective study.

ABSTRACT:

Objectives

To determine the predictors for 30-day all-cause mortality in patients with febrile neutropenia (FN) and develop a prediction score.

Methods

The electronic medical records of patients undergoing chemotherapy with FN between 2018 and 2019 were reviewed. Multivariate logistic regression was performed to identify factors associated with 30-day all-cause mortality to develop a parsimonious model. A prediction score was developed from the model's coefficients of each predictor.

Results

There were 273 FN episodes in 153 patients. The overall mortality rate was 12.5%. Pre-existing cardiovascular disease (OR 22.45), alteration of consciousness on admission (OR 18.50), anemia (OR 4.33), acute kidney injury (AKI) (OR 13.15), causative pathogen identified (OR 8.68), i

SUBMITTER: Sereeaphinan C 

PROVIDER: S-EPMC9216401 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature