Invasive group A streptococcal disease in pregnant women and young children: a systematic review and meta-analysis.

ABSTRACT:

Background

The incidence of invasive disease caused by group A streptococcus (GAS) has increased in multiple countries in the past 15 years. However, despite these reports, to the best of our knowledge, no systematic reviews and combined estimates of the incidence of invasive GAS have been done in key high-risk groups. To address this, we estimated the incidence of invasive GAS disease, including death and disability outcomes, among two high-risk groups-namely, pregnant women and children younger than 5 years.

Methods

We did a systematic review and meta-analyses on invasive GAS outcomes, including incidence, case fatality risks, and neurodevelopmental impairment risk, among pregnant women, neonates (younger than 28 days), infants (younger than 1 year), and children (younger

SUBMITTER: Sherwood E 

PROVIDER: S-EPMC9217756 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature