Estimation of secondary cancer projected risk after partial breast irradiation at the 1.5 T MR-linac.

ABSTRACT:

Purpose

For patients treated with partial breast irradiation (PBI), potential long-term treatment-related toxicities are important. The 1.5 T magnetic resonance guided linear accelerator (MRL) offers excellent tumor bed visualization and a daily treatment plan adaption possibility, but MRL-specific electron stream and return effects may cause increased dose deposition at air-tissue interfaces. In this study, we aimed to investigate the projected risk of radiation-induced secondary malignancies (RISM) in patients treated with PBI at the 1.5 T MRL.

Methods

Projected excess absolute risk values (EARs) for the contralateral breast, lungs, thyroid and esophagus were estimated for 11 patients treated with PBI at the MRL and compared to 11 patients treated with PBI and 11 patients

SUBMITTER: De-Colle C 

PROVIDER: S-EPMC9217770 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature